Current Affairs Coronavirus Thread - Serious stuff !!!

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In fairness my missus did that. She didn't post it on open Facebook though, just sent it to a few close friends and family. Unfortunately the photo included me with a full on bonnet complete with fringe over my eyes. Her mate said I looked like Grumio from Plebs. lol

Pay me a tenner and I'll give you a short back n sides lol
 
Where's that mate?

I'm just back from the local pub. Me and the missus had a couple of pints after being out for a walk and a bit of food shopping. Our pub was busier than expected, although a quite a few of tables were taken by out of towners who must have booked some self catering accommodation. Still, there were a couple of tables free,

To be fair that's Bristol City Centre, might be slightly more calm further out.

All down Kings Street completely rammed, past the Apple, back round past Brewdog and back to the harbour.

I asked if i could sit on the one free table at Brewdog and the waitress looked at me like i was insane then offered to sell me a takeaway pint to drink in the street instead which i politely declined.
 
Well, three of us at an ‘Irish’ pub with all the tables fully booked, apart from the smoking area which we non smokers nabbed, and enjoyed a couple of pints in the sunshine. Beer was ok-ish and the conversation excellent, but it got a bit chilly after 6.30pm. It was however all very civilised and enjoyable. Mind you those who had booked tables and started turning up after 6 will be feeling the chill by now......and that fella with the orange face, on the bike screaming at us, nearly put me off my pint......
 
Researcher tracked more than 10,400 care home residents in England (with an average age of 86) between December and March, comparing the number of infections occurring in vaccinated and unvaccinated groups – using data retrieved from routine monthly PCR testing.

Both vaccines reduced the risk of infection by about 56% at 28-34 days after the first dose, and 62% at 35-48 days. The effect is maintained for at least seven weeks, the authors concluded in their analysis, which has not yet been peer-reviewed.

This data is notable, given older adults with underlying illnesses have largely been excluded from vaccine trials. It also supports the UK’s decision to extend dose intervals beyond what was studied in clinical trials.

The beneficial impact on transmission was further bolstered by the findings of a lower viral load in positive tests post-vaccination – if there is less viral material detected, that suggests a lower level of infectiousness, which is linked to transmissibility.
 
Researcher tracked more than 10,400 care home residents in England (with an average age of 86) between December and March, comparing the number of infections occurring in vaccinated and unvaccinated groups – using data retrieved from routine monthly PCR testing.

Both vaccines reduced the risk of infection by about 56% at 28-34 days after the first dose, and 62% at 35-48 days. The effect is maintained for at least seven weeks, the authors concluded in their analysis, which has not yet been peer-reviewed.

This data is notable, given older adults with underlying illnesses have largely been excluded from vaccine trials. It also supports the UK’s decision to extend dose intervals beyond what was studied in clinical trials.

The beneficial impact on transmission was further bolstered by the findings of a lower viral load in positive tests post-vaccination – if there is less viral material detected, that suggests a lower level of infectiousness, which is linked to transmissibility.

I think the moral of the story is, take the jab.....
 
Researcher tracked more than 10,400 care home residents in England (with an average age of 86) between December and March, comparing the number of infections occurring in vaccinated and unvaccinated groups – using data retrieved from routine monthly PCR testing.

Both vaccines reduced the risk of infection by about 56% at 28-34 days after the first dose, and 62% at 35-48 days. The effect is maintained for at least seven weeks, the authors concluded in their analysis, which has not yet been peer-reviewed.

This data is notable, given older adults with underlying illnesses have largely been excluded from vaccine trials. It also supports the UK’s decision to extend dose intervals beyond what was studied in clinical trials.

The beneficial impact on transmission was further bolstered by the findings of a lower viral load in positive tests post-vaccination – if there is less viral material detected, that suggests a lower level of infectiousness, which is linked to transmissibility.

Care home residents in the U.K. still only have 1 dose? With 56%-64% reduced risk rate, that lasts for seven weeks, what happens after that? Say in week 8.- I’m not sure that’s such a great outcome or approach. Surely a case to be made for double dosing those LTC residents over those in their 40/50s.

Over here (Ireland), has seen a 97% reduction in Covid incidence in long term residential care with a two dose strategy of the MRNA’s as per the 21 days advice.

They are interesting comparrisons, while the U.K. approach has clearly enabled a reduced societal case incidence, i wonder is there a moral question for two dosing the likes of LTC residents to increase protection and continue to single dose the rank and file - that said you could have the knock on effect of risk reduction in LTC, if more in society are vaccinated as overall cases reduce and as such transmissibility. I’m arguing with myself now.

All very interesting......goes back to what you said earlier about no right linear approach to national rollout.
 
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Care home residents in the U.K. still only have 1 dose? With 56%-64% reduced risk rate, that lasts for seven weeks, what happens after that? Say in week 8.- I’m not sure that’s such a great outcome or approach. Surely a case to be made for double dosing those LTC residents over those in their 40/50s.

Over here (Ireland), has seen a 97% reduction in Covid incidence in long term residential care with a two dose strategy of the MRNA’s as per the 21 days advice.

They are interesting comparrisons, while the U.K. approach has clearly enabled a reduced societal case incidence, i wonder is there a moral question for two dosing the likes of LTC residents to increase protection and continue to single dose the rank and file - that said you could have the knock on effect of risk reduction in LTC, if more in society are vaccinated as overall cases reduce and as such transmissibility. I’m arguing with myself now.

All very interesting......goes back to what you said earlier about no right linear approach to national rollout.
Yeah, that statement “it supports Uk decision to delay doses” wasn’t as clear cut to me either. Would have been really nice to have a control arm so the two regimens could have been directly compared in same setting rather than having to use other countries like Ireland/Israel.

On a more positive note this is the sort of data collection I was concerned might not happen as there wasn’t an explicit formal trial.
 
Researcher tracked more than 10,400 care home residents in England (with an average age of 86) between December and March, comparing the number of infections occurring in vaccinated and unvaccinated groups – using data retrieved from routine monthly PCR testing.

Both vaccines reduced the risk of infection by about 56% at 28-34 days after the first dose, and 62% at 35-48 days. The effect is maintained for at least seven weeks, the authors concluded in their analysis, which has not yet been peer-reviewed.

This data is notable, given older adults with underlying illnesses have largely been excluded from vaccine trials. It also supports the UK’s decision to extend dose intervals beyond what was studied in clinical trials.

The beneficial impact on transmission was further bolstered by the findings of a lower viral load in positive tests post-vaccination – if there is less viral material detected, that suggests a lower level of infectiousness, which is linked to transmissibility.

Just reading this again, in terms of the overall, one dose roll out.

I know the study isn’t peer reviewed, but reading that it seems to indicate, there have been positive cases on a growing scale 7 weeks post first dose vaccination for those who received one dose- declining immunity, with a however lower viral load.

Im mining and interpreting that data I know , but does it indicate the timeline and risk proportion of the one dose strategy to future transmission, if applied to the general population. I.E from seven weeks post dose 1 to second dose at 12 weeks, there is decreased protection - sorry I know i making big leaps there and interrupting, perhaps assuming but it’s one of the first things I’ve seen data wise, on the break out of the U.K. one dose strategy and impact on immunity.
 
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