I was listening to the radio before and it claimed that research estimates that 25% of COVID-19 deaths in the UK have diagnosed or undiagnosed diabetes.
The data shows that you're 20% more likely to be admitted if you're obese, and if you are admitted then you're approximately 40% more likely to die.
Here are a couple of links exploring the relationship with diabetes, the second is a speculative idea (especially fhe Hydroxychloroquine bit) but it has given me extra motivation skip the sugary breakfast and to do my morning exercise!
Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interven…
www.sciencedirect.com
Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. Thus, we performed a retrospective, multi-centered study of 7,337 cases of COVID-19 in Hubei Province, China, among which 952 had pre-existing T2D. We found that subjects with T2D required more medical interventions and had a significantly higher mortality (7.8% versus 2.7%; adjusted hazard ratio
, 1.49) and multiple organ injury than the non-diabetic individuals.
Further, we found that well-controlled BG (glycemic variability within 3.9 to 10.0 mmol/L) was associated with markedly lower mortality compared to individuals with poorly controlled BG (upper limit of glycemic variability exceeding 10.0 mmol/L) (adjusted HR, 0.14) during hospitalization. These findings provide clinical evidence correlating improved glycemic control with better outcomes in patients with COVID-19 and pre-existing T2D.
What does high blood sugar have to do with vulnerability to COVID-19? And is there a role for the controversial drug hydroxychloroquine in lowering blood sugar in COVID-19 patients?
theconversation.com
The new coronavirus infects cells by attaching to the surface through a receptor called the angiotensin converting enzyme 2, or ACE2. Both the ACE2 and the virus need sugar molecules bound to their protein for this to work properly.
My idea, which I have
described in a peer-reviewed article in the Journal of Medical Virology, is that COVID-19 infection and its severity is influenced by the concentration of sugar-coated virus and the concentration of sugar-coated ACE2 receptors in the lung tissues. The degree and control of the lungs’ immune response may also depend on how much sugar is attached to virus’s spike protein approximately eight to 10 days after symptoms start, which may
vary depending on your age and se
...
High blood sugar increases the number of sugar-coated ACE2 receptors in the lungs of diabetic mice. So not only are the number of receptors greater, but also there are more sugars attached to them. This makes it easier for the virus to infect cells. When there is more insulin, or through diet or exercise, there is less sugar, so there are fewer ACE2 receptors and less sugar on each one, and this may reduce the amount of virus getting into the cell.