Is it true spoons buy out of date stuff and stuff near its sell by date ??
Current Affairs Coronavirus Thread - Serious stuff !!!
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roydo
in memoriam - 1965-2024
You got a Chinese/Thai/etc takeaway near by that might have some? Or perhaps ask a corner shop if they would get some ordered in specially?
When it was a bit mental, shop wise, I asked my local corner shop if they would keep some bananas aside for me, cos my old man needs them. Not a problem. (Think they were quite chuffed to be asked if I am honest).
edit. Or search the ready meals in the supermarket?
Foot Long Hot Dog
Player Valuation: A packet of pork scratchings
Only the main Nightingale facility hasn’t got the correct level of ICU trained resource, which is what I clearly said in the first post you replied to. So, it’s not been able to take critical care overspill from the local hospitals. I’ve no idea where you’ve pulled the 50% stat from or even what you’re suggesting it refers to.
our chinese do
Boiled rice (white )
Egg fried rice (white )
Fance yung chow rice ( white )
I think they keep the good stuff for themselves
Tried all the local shops
I can get own brand Brown rice but it takes 20 mins to cook and tastes crap
PS I only buy brown wholemeal pasta except when I buy fresh pasta as a treat
Staffed with who exactly would be an interesting discussion point.
I always wonder who these people are who get two servings out of that , also the people who get multiple servings out of yoghurts . Not to be trusted these types in my opinion .
Not experienced in drug trials but changing the measured endpoint mid trial seems a bit odd.
blogs.sciencemag.org
Now we have bits of data from an NIAID/NIH trial of the drug that began enrolling in Nebraska in late February (the first patient was one of the Diamond Princess cruise ship passengers, which seems long enough ago by now that it might as well be the Titanic). This one was double-blinded and placebo-controlled: patients in the treatment group received 200mg of the drug the first day and 100mg each day thereafter, for up to ten days. Participants needed to test positive for the virus and have evidence of lung involvement in the disease. The primary endpoint was improved time to recovery (discharge from the hospital or ability to return to normal activity), and it appears that remdesivir was statistically better than placebo: 11 days versus 15 days. The team also monitored overall survival in the >1000 patients, and there was a possible trend towards the drug, but it did not reach statistical significance (8% mortality in the treatment group, 11.6% in the placebo group).
That’s it. Those are the numbers we have. The rest will be in a “forthcoming report”, and we’re going to have to wait until it comes forth. This release was after an April 27 meeting of the data and safety monitoring board, and it’s worth noting that had there been “clear and substantial evidence of a treatment difference” during the trial that the DSMB was to have halted the study at that point. We can infer that nothing rose to that level, then: we have a difference, but not substantial enough to have ended the trial prematurely. And I have to note another issue: if you look at the Clinicaltrials.gov record for the trial, it appears that the outcomes measures for the trial were changed (as noted by Walid Gellad on Twitter). That primary endpoint of the trial mentioned above, time to recovery? It was originally an 8-point severity scale (death, on ventilator, hospitalized with oxygen, all the way down to discharged with no limits on activity). A similar ordinal scale measure is still in the secondary endpoints, as it was before, but we have no numbers for that yet, of course. But it’s clear that the primary endpoint was changed at some point in April.
About Remdesivir and About "Game-Changers"
We've had several releases of remdesivir data, and this was not exactly one of those controlled-release formulations. No, this was more in the "chaotic mess" category, with news items coming from several sources with partial information. I decided not to blog on it until the loud banging noises stop
blogs.sciencemag.org
That’s it. Those are the numbers we have. The rest will be in a “forthcoming report”, and we’re going to have to wait until it comes forth. This release was after an April 27 meeting of the data and safety monitoring board, and it’s worth noting that had there been “clear and substantial evidence of a treatment difference” during the trial that the DSMB was to have halted the study at that point. We can infer that nothing rose to that level, then: we have a difference, but not substantial enough to have ended the trial prematurely. And I have to note another issue: if you look at the Clinicaltrials.gov record for the trial, it appears that the outcomes measures for the trial were changed (as noted by Walid Gellad on Twitter). That primary endpoint of the trial mentioned above, time to recovery? It was originally an 8-point severity scale (death, on ventilator, hospitalized with oxygen, all the way down to discharged with no limits on activity). A similar ordinal scale measure is still in the secondary endpoints, as it was before, but we have no numbers for that yet, of course. But it’s clear that the primary endpoint was changed at some point in April.
I never really understood where they drew the line between Pathway and Euthanasia.
My mum went on pathway. She'd had a stroke and the muscles in her throat wouldn't allow her to swallow. They couldn't force feed her either as she had a hiatus hernia. So she was basically just taking vitamins and fluids intravenously. She was 90 at the time but had been very ill for a number of months The family were offered pathway and we agreed (all six of us which was probably a first). She was removed from the drips the following day and we were told that it would take about 4/5 days before she passed on. Over a week later and she's still going strong. My sister works in the hospital so was spending a lot of time daily with her, and one day when she went into her room one of nurses was holding a lolly ice for her to suck. She's thirsty the nurse says guiltily, not even sinking in that my mum shouldn't even be able to swallow.
So my sister get's the doctor who brings in the speech therapist who declares her throat muscles are working again. So they immediately put her on liquidised foods and she's taken off pathway. Apparently it was a double miracle. Firstly the use of her throat muscles returning, and secondly surviving 9 days without food and water given the state of her health when she went onto pathway. The medical staff were amazed.
It must have been the Irish in her. She's from Naas.
After that ordeal though little wonder she only lasted 3 months in the care home.
Jeepers thats some story and experience mate, good Palliative care seeks neither to hasten or delay end of life but support the natural progression and maximize comfort holistically and holistic quality of life in between, but in every case you need good clinical judgement in regard to someones illness trajectory and what approach is apt. I would be lying if i said i haven't seen and experienced similar sudden deterioration's and unexpected temporary recoveries, some just defy logic, in an amazing way to keep us all humble. Its what i meant yesterday about us that work in healthcare sometimes supporting or projecting frailty in health care and on outcomes, we can make judgments based on someones profile and decisions overtly that can impact clinical trajectory. While as i say its sometimes less about concept or philosophy and sometimes about the skills and values of a team implementing it.
A little bit of Naas will do you no harm either, your Mam was a Lillywhite as we call people from Kildare, im no stranger to Nass, funnily i was 10 mins outside it today on my way into work, ill give the town your Mams best the next time i'm there.
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Barnfred 55
Player Valuation: £80m
That's very reassuring to hear.
But most, not all, but most of the people in nursing homes are there because they can no longer be looked after at home or in sheltered accommodation. Most are already very poorly either with some form of dementia or are infirm to some degree. The death rate would be a lot higher becaue of this and it's why care homes are showing such high numbers.
I'm not sure if it's bad news that a third of homes have been infected by the virus, or good new that two thirds have so far avoided it.
I eat the full bag and still want more
Barnfred 55
Player Valuation: £80m
Lillywhite eh?Jeepers thats some story and experience mate, good Palliative care seeks neither to hasten or delay end of life but support the natural progression and maximize comfort holistically and holistic quality of life in between, but in every case you need god clinical judgement in regard to someones illness trajectory and what approach is apt. I would be lying if i said i haven't seen and experienced similar sudden deterioration's and unexpected temporary recoveries, some just defy logic, in an amazing way to keep us all humble. Its what i meant yesterday about us that work in healthcare sometimes supporting or projecting frailty in health care and on outcomes, we can make judgement s based on someones profile and decisions overtly that can impact clinical trajectory. While i say its sometimes less about concept or philosophy and sometimes about the skills and values of a team implementing it.
A little bit of Naas will do you no harm either, your Mam was a Lillywhite as we call people from Kildare, im no stranger to Nass, funnily i was 10 mins outside it today on my way into work, ill give the town your Mams best the next time i'm there.
She kept that quiet.
peteblue
Welcome back Wayne
I believe they get it close to the best before date. And why not, they can shift it quicker than anyone else and can negotiate better prices. The stuff they sell is good quality at prices few can match......
Ohh We’ve got a Video . Like when you’re a kid and you’ve not done enough on your project and you pad it out with meaningless stuff to save you having to do any more .
Thats the nice term.
The flour bags - is another if you are a Dub (which i am) and comes to GAA.The nickname for the Kildare GAA team is the Lilywhites, This is as a result of early jerseys being made from the bags of the Lilywhite Bakery. The all-white jerseys they wear are in reference to this.
In 1928, Kildare became the first team to win the Sam Maguire trophy for the All-Ireland Senior Football Championship, defeating Cavan 2–6 to 2–5. However, since then Kildare have reached the All-Ireland Football Championship Final on four occasions, the last being in 1998, but have failed on all four attempts.
County Kildare is also known as the Shortgrass County which is a reference to how short the grass is on the commons of the Curragh.
BlueStevie35
Player Valuation: £70m
Claiming we are past the peak and the R is below 1 now
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