I think I'm with @bluesteven on this one mate. Even if Schneids is fit, which I think is looking doubtful, I'd still be looking to play 3 at the back against both RS and the Mancs. But I would definitely start with Holgate, Williams and Funes Mori. All three suit the system far better than a back 4 and, with the exception of 45 mins against Stoke when Holgate was targeted by Crouch, have looked very comfortable together. You're not going to get that threat against Liverpool, and I also doubt if Man U will employ it either, though they are a lot more capable of doing so.
I'm not sure who I would play at right wing back. I think Lennon could do a job there but I think it's time to give Jonjoe a run in the team. I'm pretty certain he won't let us down. He's a good defender but also likes to get forward too. His distribution is good but he won't give you that threat that Seamus does, but then again, who else in the premier does?
I'm just not sure throwing a lad who has one PL appearance in to the derby and then a trip to OT is the way to go mate... Or, more accurately, I'm not sure Koeman will think that's the way to go...
Lennon won't be put into that position.
If Macca is fit then maybe yes, but I can't see him making it for the RS at least...
We'll see anyway.