Japan isolated itself from the world until 1854; within 40 years of it being forced to open up (By the good ol' US of A, no less) it became one of the most belligerent nations on the planet, and is still (to date) the only country to have suffered nuclear attacks.
But they're now the world's 2nd biggest economy, so that makes it alright.
They were still 'loonies' when they were isolated, though.
Japan is doomed as a country due to its low birth rate.