Current Affairs Coronavirus Thread - Serious stuff !!!

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Deckard2049 said:
Semi serious question as I don’t think it will happen but hypothetically, let’s say the Indian variant caused a delay in the reopening. Surely at this point the government would have to take full responsibility for this and would owe thousands if not millions in compensation to businesses forced to stay closed or alter their plans for trading if said businesses pursued claims? Or would they just pass it off as an “unfortunate setback” with Boris using his favoured “alas there was nothing we could do”.

Yes, a pandemic is an act of god. But this isn’t March 2020 anymore. At some point the government has to take responsibility (I know, I know) for its policies, actions (or lack thereof) massively effecting the people of this country. Not closing borders when the warning signs are there has damaged us before and it seems they still haven’t learned their lessons. It’s 2021, we see footage and hear reports from all around the world every hour of every day. It’s not like the bbc had to send David Frost over to India for a 6 o clock special to draw attention to the situation.

Maybe the Indian variant would have reached us anyway, but hopefully it would have done so after our first doses had massively ramped up again. The damage this could do to businesses and the populations mental well being would be ginormous.
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It would be billions - and yes, it's purely their fault that this variant has found it's way to our shores

Just bring in localised lockdowns again for Greater Manchester and Glasgow
 
LinekersLegs said:
Tbf it probably isn’t all down to the vaccines, in early days of an outbreak we typically see the case numbers go up for younger people as they tend to have more interactions.

But that flat line in the fully vaccinated over 80s is very encouraging, especially when matched with the nursing home data we had on the effectiveness of vaccines on this variant.

What would be really great is if we could surge vaccines to Bolton for all age groups and we’d hopefully see those case numbers even in the younger cohorts come down in ~10 days post vax
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But doesn't it take 3 weeks to become effective Legs. Also O do believe we have mainly the AZ jab available and we're not giving that to the under 30s.

TBH, if it wasn't for that I'd be giving priority to the under30s now.
 
Barnfred 55 said:
But doesn't it take 3 weeks to become effective Legs. Also O do believe we have mainly the AZ jab available and we're not giving that to the under 30s.

TBH, if it wasn't for that I'd be giving priority to the under30s now.
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It depends on whether you are meaning full or partial protection. Early on there is little difference between a partially or unvaccinated person on their chance of getting COVID but at 7-10 days the two lines start to gradually diverge. So a person at three weeks post vax is going to have much more protection than a person at two weeks but the latter is still going to have better protection than an unvaccinated one.

Obviously further protection is then provided by the second dose and there will be differences across individuals but if I understand the data correctly I’d be expecting to see some topping of infection rates start around 10 days with the effects then increasing as more days past.
www.thelancet.com

Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study

Systemic and local side-effects after BNT162b2 and ChAdOx1 nCoV-19 vaccination occur at frequencies lower than reported in phase 3 trials. Both vaccines decrease the risk of SARS-CoV-2 infection after 12 days.
www.thelancet.com
We observed that 5–11 days after vaccination, the infection rates in the vaccinated group were only slightly below those of the unvaccinated group (figure 4), whereas 12–20 days after vaccination, infection risk in the vaccinated group was significantly lower than in the unvaccinated group (RR for BNT162b2 −58% [95% CI −62 to −54]; RR for ChAdOx1 nCoV-19 −39% [95% CI −53 to −21]), after adjusting for population differences in the vaccinated groups using Poisson regressions. We observed a further reduction in infection risk after one dose of the BNT162b2 vaccine when compared with unvaccinated controls at 21–44 days after vaccination (RR −69% [95% CI −72 to −66]) and at 45–59 days after vaccination (−72% [–79 to −63]; figure 4). The RR after one dose of ChAdOx1 nCoV-19 compared with unvaccinated controls was −60% (95% CI −68 to −49) at 21–44 days after vaccination.
 
RAFUH said:
Doesn't sound great in a headline until you realize that could mean a larger immune response
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Yeah will be keeping an eye out for the followup in a few weeks by the rather unfortunately named professor.
“It’s a really intriguing finding and not something that we were necessarily expecting,” said Matthew Snape, an Oxford pediatrics and vaccinology professor who’s leading the trial. “Whether or not this will relate to an improved immune response, we don’t know yet; we’ll be finding out those results in a few weeks’ time.”
Full link for those interested
www.thelancet.com

Heterologous prime-boost COVID-19 vaccination: initial reactogenicity data

There is significant international interest in heterologous prime-boost COVID-19 vaccination to mitigate against supply shocks or shortages that might otherwise reduce the speed of vaccine roll-out. Additionally, in light of changing recommendations regarding use of the ChAdOx1 nCoV-19 (ChAd)...
www.thelancet.com
 
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