davek
Player Valuation: £150m
Fingers crossed.
Current Affairs Coronavirus Thread - Serious stuff !!!
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BlueStevie35
Player Valuation: £70m
But its not a political decision is it? It's more a 'we can't afford to pay it back' decision as most pubs either don't have a garden facility or are backed by a name chain
Obviously hope they do but also going to be interesting to see which vaccine they choose - iirc UK recommendations are now for under 40s to have the Pfizer but get the feeling there is more flexibilty in AZ supply.@LinekersLegs
Andy Burnham, the mayor for Greater Manchester, has said the Joint Committee for Vaccines and Immunisations is considering a request to vaccinate all over-16s in Bolton in response to the rising infection rate.
Indian Covid variant calls in question 17 May reopening in UK, say experts
Highly transmissible B.1.617.2 is now second most common variant and is spreading in north-west Englandwww.theguardian.com
Personally I think the risk/reward is in favor of using whichever you can get into arms quickest, especially this particular variant which may have worse outvomes in yoing adults anyway, but if they do use AZ and there are a spike in blood clot cases then it could potentially impact raise vaccine hesitancy overall.
I honestly havent seen anything about clots for a while.
I know you have posted a few things, but it seems like we are trying to make people forget over here.
As you know, media drives everything.
I personally think that is the wrong approach. I prefer to be open and honest about data anyway and feel it is the best long term policy (despite some short term impacts) as it builds trust and hopefully tamps down conspiracy theories.
Especially as in this case the risks are low to start with and you are likely to reduce them further with an informed population/medical community.
Well "we" didnt even mention them till the rest of Europe started making noise.
I dunno, I'm sure the information is out there, but I haven't come across any recent data.
Yeah how the US medical community has handled JnJ clot data (and previously the mRNA allergy reaction) has been dramatically different to how the UK handled AZ clotting data. One benefit of having a paranoid population?!
You are offering people 1million bucks for vaccines over there, quite mad the difference between 2 nations, that in my younger days, I always considered were quite similar.
You said the last lockdown wasn't strict enough, and plenty of others did too tbf. Schools opened up two months back, people were able to play team sports at the end of March, have now had four weeks of mixing in beer gardens, going into shops etc
We haven't been in 'lockdown' for over a month now, yet cases have completely dropped to lower than they were last summer. The small spikes we have seen are in age groups that probably have less people vaccinated in general.
There's plenty of evidence that it's now both the impact of the last lockdown and the impact of the vaccines
Doesn't sound great in a headline until you realize that could mean a larger immune response
cahill007
Player Valuation: £225k
I got my Pfizer jab today, i am 27 and live in NZ.
Was a complete accident, i was taking my 6 week old for her first jabs (not fun) and the nurse asked my wife and I, if we would like a covid shot as they were going to expire.
(i am in bottom priority group so i didn't really want it, as I don't like the idea of taking it before someone who needs it and in nz the needs is very low. It was 5:30 though and she said if i didn't take it was going in the rubbish's as needed to be used within the next 2 hours.
The nurse said once the vaccine was unpacked they had 6 hours to administer them, and 4 people has not shown up for their appointment today
so i stuck my arm out as not wanting it to go to waste.
Anecdotal i know, but it made me wonder how much of that was happening around the world?
Was a complete accident, i was taking my 6 week old for her first jabs (not fun) and the nurse asked my wife and I, if we would like a covid shot as they were going to expire.
(i am in bottom priority group so i didn't really want it, as I don't like the idea of taking it before someone who needs it and in nz the needs is very low. It was 5:30 though and she said if i didn't take it was going in the rubbish's as needed to be used within the next 2 hours.
The nurse said once the vaccine was unpacked they had 6 hours to administer them, and 4 people has not shown up for their appointment today
so i stuck my arm out as not wanting it to go to waste.
Anecdotal i know, but it made me wonder how much of that was happening around the world?
It has happened a lot...and that's just two pharmacy chains.
You did the right thing. Better in an arm than wasted.
cahill007
Player Valuation: £225k
that's sad to think of how much of a benefit those wasted doses would have been to somewhere like India
Public health impact of delaying second dose of BNT162b2 or mRNA-1273 covid-19 vaccine: simulation agent based modeling study
Objective To estimate population health outcomes with delayed second dose versus standard schedule of SARS-CoV-2 mRNA vaccination. Design Simulation agent based modeling study. Setting Simulated population based on real world US county. Participants The simulation included 100 000 agents...
This was most significant when the second dose was delayed in people below 65 years of age, with second doses still prioritized for those over 65. The conditions in which these benefits were observed included the first dose vaccine efficacy being above 70% and vaccination rates remaining below 1% of the population per day. These two conditions seem reasonable on the basis of the CDC’s estimate of first dose vaccine efficacy being 80% and only a couple countries such as the US reaching a vaccination rate close to 1%.7172122 The timeframe of 180 days used in our study was thought to be important to policy makers who face the immediate challenge of increasing their population immunity by increasing vaccination rates but also balancing these decisions with the lack of data on sustained vaccine effectiveness beyond this period.
Our findings suggest that vaccination rate is an important factor in choosing a strategy. A delayed second dose strategy either in people below 65 years old or the entire population did not show a cumulative mortality benefit compared with an on-schedule two dose regimen when the vaccination rate was 1% of the population or above. At very low vaccination rates, the differences in delay strategy were not observed but favored delays in people aged 65 years and younger when rates were 0.3% to 1% of the population per day. Our findings also suggest that changes in cumulative mortality are larger than the corresponding decrease in the number of infections. For example, the relative reduction in the cumulative number of infections for a vaccination rate of 0.3% and a first dose efficacy of 80% is around 6%, whereas the reduction for mortality is 11%.
These results may be broadly informative for covid-19 vaccine strategy. Other than a select few countries such as the US and UK, vaccination rates remain well below 1% of the population per day. The strategy in most locations continues to be a strict two dose schedule for either the BNT162b2 or mRNA-1273 vaccine. The vaccination rates used in our study ranged from 0.1% to 1%, which represents a large range of observed rates and is therefore likely to be useful for policy makers in various countries globally. With the continued large death toll from covid-19 and reports of mutant strains, each country is facing increasing urgency to vaccinate its population rapidly.23 The multiple vaccines in phase III trials offer promise for increasing availability and therefore vaccination rates, but BNT162b2 and mRNA-1273 still account for a large portion of the world’s covid-19 vaccine supply.1324 The strategy of delaying the second dose has been an active discussion given its ability to rapidly increase covid-19 immunity in the population by increasing single dose vaccination rates, but empiric research to understand its implications was lacking.
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