Current Affairs Coronavirus Thread - Serious stuff !!!

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Flu jab? The jab that's been around decades and is tweaked every year with a mountain of evidence to draw on and that is proven to give over 50% protection? Yes.

It's a different matter all together with a vaccine tested on handfuls of people.

But you said you wouldnt believe a word from anyone in the UK re this vaccine. But believe what they told you about the flu jab.
 
Feels political, but it's probably more to do with differing clinical interpretations. UK has seen immunogenicity in studies and thought it's enough, Germans clearly place more emphasis on proven efficacy. Which is... fine I guess, but you'd think given emergency situation that a bit more sense would prevail in terms of authorising the vaccine and it'll be given across the board.
You are also dealing with different rates of vaccine hesitancy in the population.

Being able to demonstrate that you have dotted all the i’s and crossing all the t’s could well make a difference in uptake and avoid damaging rumors starting that may outweigh any potential gains to be had by early approval.

There are also different legal environments - a lot of the vaccinations in the US will by private companies so liability becomes a factor.
 
"Calculations in the German authorities’ draft recommendation show only 6% of participants in the trials were over 65, with 341 of them receiving a shot of the AstraZeneca vaccine and 319 receiving a placebo.

In the trial, one infection was recorded in the treatment group and one in the placebo group, creating a high confidence interval that the German authorities described in their report as “no longer statistically significant”. They said: “Any assessment about the efficacy of the vaccination among the highest age group (≥75 years) therefore comes with a high level of uncertainty.”
 
But you said you wouldnt believe a word from anyone in the UK re this vaccine. But believe what they told you about the flu jab.

The flu jab is international in nature. It works. It's worked for years. We KNOW this because there is a mountain of data to support it in the real world.

Not so AZ's jab on older groups.
 
Flu jab? The jab that's been around decades and is tweaked every year with a mountain of evidence to draw on and that is proven to give over 50% protection? Yes.

It's a different matter all together with a vaccine tested on handfuls of people.

Coronavirus isn't new, just this variant is.
"Calculations in the German authorities’ draft recommendation show only 6% of participants in the trials were over 65, with 341 of them receiving a shot of the AstraZeneca vaccine and 319 receiving a placebo.

In the trial, one infection was recorded in the treatment group and one in the placebo group, creating a high confidence interval that the German authorities described in their report as “no longer statistically significant”. They said: “Any assessment about the efficacy of the vaccination among the highest age group (≥75 years) therefore comes with a high level of uncertainty.”

Yeah we already knew that though.
 
Hospital figures - 1071 deaths were announced today, down 54 on yesterday and up 122 on last Thursday. 907 deaths were in English hospitals, down 66 on yesterday and up 118 on last week. The 7 day rolling average rises to 927.43

All settings - for the 28 day cut off, 1239 deaths were announced today, down 486 on yesterday and down 51 on last Thursday. The 7 day rolling average falls to 1220.86

For the 60 day cut off, 1337 deaths were announced today, down 566 on yesterday and down 65 on last Thursday. The 7 day rolling average falls to 1323.14
 
Coronavirus isn't new, just this variant is.
FFS. Thanks for that.
Yeah we already knew that though.


...what you didn;t know is that another regulator has dismissed it as good enough.



Look, the EU regulator may pass this for the over-65s tomorrow. Who knows.

However, this age group issue is a live one, and the US and other countries are determined to see real world data on AZ's efficacy for the elderly before they commit to it.

The UK is the laboratory.
 
FFS. Thanks for that.



...what you didn;t know is that another regulator has dismissed it as good enough.



Look, the EU regulator may pass this for the over-65s tomorrow. Who knows.

However, this age group issue is a live one, and the US and other countries are determined to see real world data on AZ's efficacy for the elderly before they commit to it.

The UK is the laboratory.

As are India and Israel.
 
FFS. Thanks for that.



...what you didn;t know is that another regulator has dismissed it as good enough.



Look, the EU regulator may pass this for the over-65s tomorrow. Who knows.

However, this age group issue is a live one, and the US and other countries are determined to see real world data on AZ's efficacy for the elderly before they commit to it.

The UK is the laboratory.

They haven't dismissed it as 'not good enough' - they've said they don't have enough data to make a firm conclusion. Which is fine.

The immunogenicity of it is proven, just not the efficacy, although at other age ranges it is - and you don't suddenly turn into a different species aged 65.

I get you hate British nationalism and the Tories, but you don't half let it put the blinkers on for your views.
 
Noticed in the interview with the AZ CEO he mentioned how Oxford Uni basically didn't want to test the vaccine on more older groups - for ethical reasons. Seems a fair approach but yeah, it's difficult.



It’s an interesting story depending on your viewpoint, the Oxford team seem at heart an ethical and humanitarian bunch. They initially wanted to donate the rights to the vaccine to anyone who wanted to produce it. A lot of cometary on why they changed their mind and AZ came in and things have become how they are, it’s quite a trajectory and I’d say an interesting story.

Maybe what’s important to point out, is drug companies don’t particularly like vaccines and many aren’t interested in them, they don’t make a lot of money, generally low cost and not very frequent - maybe once or maybe twice a year per dose. Drug company like high cost, regular drugs administered very regularly and that’s what they try and develop and sell as a priority.

There is a story to be told around this vaccine race, how things panned out and likely, motivations, company’s involved and our reactions now in the future, it’s going to be interesting.
 
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