Escaping the present box would be quite the Houdini act. Biden is better known for his gaffes. Bill Clinton might have been able to turn this political urine into wine, most likely with the aid of James Carville, but never Biden. If Biden extracts himself from the box, it will be on policy, not spin.
Who do the Democrats run, though? It almost has to be a governor, but most of them are cozied right up to Israel. Even relative fence-sitters like Beshear and Whitmer have taken an Israel trip. What can the Democrats do, run a national no-mark like Janet Mills, who is 75 and interned for an ACLU attorney? That's like the inverse function of running Sarah Palin at the top of a ticket. She's intelligent, she's well left on center (except on drug policy) and she's old.
Who else can create separation from Biden, at this juncture? Sanders is 82. He appeals to independents (after all, he is one), and I bet he beats Biden this time if he stands, but can he beat Trump? AOC turns off Republican-leaning independents like a light switch. She might win with RFK Jr. in the game, but always loses with him out of it. Schiff has the money and the profile to play, and a moderate voting record as Democrats go. He sets up well to turn a fight against Trump into a referendum on the rule of law, but that's a win-or-bust gamble for him. Does he pull the trigger, or stay the course on his Senate run against less well-funded opposition?
Per OpenSecrets.org, about the only sitting Democratic senator besides Sanders whose hands are relatively clean of pro-Israel money is Alex Padilla. He's well right of his California predecessors (though still somewhat left of center), but I don't know if he's a great campaigner. After a moderately difficult statewide race to gain the Secretary of State job in 2014, all he has done is beat serial electoral punching bag Mark Meuser three times. Most of the senators with a national profile due to tough electoral fights are up to their eyeballs in pro-Israel money, because they weren't exactly in a position to say 'no' to money from out-of-state.
The whole fiasco exposes the core problem with the modern Democratic Party, which is that it's a coalition of grievance interest groups vulnerable to fractures. They need a Bernie-lite right now, and a message with broad appeal, but Barack Hussein Obama is term limited.