Thanks. I'll be sure to do some basic research in future - so that I too can make sweeping statements about the law of declining virulence.
Current Affairs Coronavirus Thread - Serious stuff !!!
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Montgomery v Lanarkshire Health Board [2015] All ER (D) 113 (Mar).
Montgomery v Lanarkshire Health Board - Wikipedia
en.m.wikipedia.org
Nice one mate, exactly where I’m coming from - informed consent is so important, without it you just let someone else, assume risk and decision making for you.
Scary that had to go to the Supreme Court.
Barnfred 55
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Maybe absolutely safe was the wrong choice of wording. How about very safe?. I don't think anything in life is totally risk free, even sleeping. It's all about degrees of risk. In my opinion the risk of serious illness or death associated with this vaccine is very very low and not even comparable for many people with the risk of not being vaccinated.
Spadge Vernacular
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A novel variant of interest of SARS-CoV-2 with multiple spike mutations detected through travel surveillance in Africa
At the end of 2020, the Network for Genomic Surveillance in South Africa (NGS-SA) detected a SARS-CoV-2 variant of concern (VOC) in South Africa (501Y.V2 or PANGO lineage B.1.351)1. 501Y.V2 is associated with increased transmissibility and resistance to neutralizing antibodies elicited by...
Given the influence that California has on daily life (especially Hollywood and tech industry) you didn’t think we were just going to let COVID pass us by without sticking our own oar in did you?!
How weak is that new variant?A novel variant of interest of SARS-CoV-2 with multiple spike mutations detected through travel surveillance in Africa
At the end of 2020, the Network for Genomic Surveillance in South Africa (NGS-SA) detected a SARS-CoV-2 variant of concern (VOC) in South Africa (501Y.V2 or PANGO lineage B.1.351)1. 501Y.V2 is associated with increased transmissibility and resistance to neutralizing antibodies elicited by...www.medrxiv.org
Spadge Vernacular
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It carries more mutations than any other strain that has previously identified, so is a major concern.
Completely agree with everything in this post and will add that despite the side effects currently being established as rare it was also important from a response point of view - both for patients reacting to warning signs of blood clots and doctors making sure they ask “have you had the vaccine recently”. It also seems the treatment of the blood clots may be different, with standard treatment of heparin potentially making things worse.
The small chance of an allergic reaction was also important to make clear for similar reasons, so that everyone could have informed consent and that practices could be put in place to minimize its impact if it happened.
Can't be, viruses always mutate to be weaker. Simple science.
I think that’s fair, it’s incumbent on all of us to explore, understand, explain and decide on risk individually, but maybe we are speaking to generally, it all needs to be subdivided and explored in detail.
In this scenario, there is an awful lot to still assess, @LinekersLegs was hinting at it there, now we know there is a risk, we need to look at the scale of the risk, vulnerabilities and triggers in particular cohorts, age, sex, clinical background, lifestyle, etc, etc. Understanding this may help us mitigate risk and better protect people. It’s a perpetual process toward improving care, but it doesn’t happen without being upfront with acknowledging risk.
I know this is sarcasm, but they have said from the start that this virus isn't like most others, it changes, but it also never changes much.
Basically it retains its memory.
Created in a lab mate. Proof.
Barnfred 55
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That's exactly why I said we should be spending the next 2 months investigating the link between AZ and blood clots, so we can get a much more accurate picture of who's at risk and to what extent, rather than make a kneejerk decision to stop it for a whole demographic of the population.
My understanding mate on some of the data available is the risk increases from 60-55 down, soon that basis until we know more it seems the clever play to me.
This virus is incredible in terms of contradictions, the older you were the more vulnerable you were, now with the AZ vaccine it may be the younger you are the more vulnerable to risk from a vaccine.
Spadge Vernacular
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I know why you are saying this but it's a factually incorrect statement. Viruses are subject to natural selection in the same way that other life forms are, though they require a host to provide a living environment. If we consider influenza we can see that they evolve gradually through mutations to their surface in order to hide from our immune systems - a disguise of sorts. Without this evolving antigenic drift, (and shift when two mutations combine) the virus is at risk of failure, which can be a limitation for some, but not for the flu, common cold, norovirus, HIV, etc, and sadly looking to be not true for covid-19 which is display the ability to mutate rapidly.
If you look at this article about the new mutation in Africa you'll see they talk about covid "evolving under positive selection and improving viral fitness"
Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa
Scientists recently explored the transmission dynamics of currently circulating variants of SARS-CoV-2 in a southern African country. By analyzing the genomic sequences of these variants, they have identified a novel SARS-CoV-2 variant with multiple spike mutations. They have temporarily...
www.news-medical.net
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