Current Affairs Coronavirus Thread - Serious stuff !!!

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I dunno. I have no idea if Brazil have a history of CV type infections. I guess, like most things, there will not be ONE reason why populations cope differently, but a petri dish of all sorts.

But I struggle to square the circle why British born Asians are high risk here, while in India billions have shrugged it of. It seems. Could be anything. My theory just has a strand of admittedly my logic.
In India there's a distinction between urban and rural response to Covid19. Most British Asians are urban.
 
Tests with the AZ vaccine have produced promising results with the 12 week interval meaning a stronger response than just 21 days. The Pfizer data from Israel published yesterday suggest much the same is probable and a strong effectiveness will still be maintained after 12 weeks.

No, it doesn't - the trial stopped after four weeks.
 
Amazing.

I took comfort when I read/heard that there are 3000 proteins in a CV virus, and the folk know what ones do what, based on past experience. So thats the starting game.

I guess its like I know jack about cars. Can drive one, inflate tyres, top up oil, and thats it. So a problem to me, is straight forward to a good mechanic.

Thats my comfort blanket, all things Covid.
SARS gave the Oxford team (and others) a head start, almost a blessing in disguise.
 
No, it doesn't - the trial stopped after four weeks.
Well it does really...

It stopped after 4 weeks but the levels of response attained meant it highly likely that there would still be effective immunity for a long time afterwards.

The higher the response attained the more likely it will last at viable levels for some time afterwards. Vaccine induced immunity doesn't just fade overnight, it takes some time for the body to stop producing such antibodies.

A decent analogy is that the body's immune response has been switched on, antibody production has started and has been revved up, it takes time before the body even stops producing more, never mind those already in circulation 'flushed out'. Experience with other vaccines, although not like with like, do give a decent and likely guide to possible timescales. Even in the worst scenarios to have such a strong response after 4 weeks is very encouraging.
 
Well it does really...

It stopped after 4 weeks but the levels of response attained meant it highly likely that there would still be effective immunity for a long time afterwards.

The higher the response attained the more likely it will last at viable levels for some time afterwards. Vaccine induced immunity doesn't just fade overnight, it takes some time for the body to stop producing such antibodies.

A decent analogy is that the body's immune response has been switched on, antibody production has started and has been revved up, it takes time before the body even stops producing more, never mind those already in circulation 'flushed out'. Experience with other vaccines, although not like with like, do give a decent and likely guide to possible timescales. Even in the worst scenarios to have such a strong response after 4 weeks is very encouraging.

No, it doesn't. You say "a long time" and then "for some time", which kind of demonstrates that we do not know at what rate the protection from a first dose will decline, how long it will take to decline and so on. I'd have hoped that a government would want to find that out before deciding a policy, but it seems not

We already knew one dose of it would give a decent amount of protection - thats what the first studies found - but how long it lasts is still the unknown.
 
No, it doesn't. You say "a long time" and then "for some time", which kind of demonstrates that we do not know at what rate the protection from a first dose will decline, how long it will take to decline and so on. I'd have hoped that a government would want to find that out before deciding a policy, but it seems not

We already knew one dose of it would give a decent amount of protection - thats what the first studies found - but how long it lasts is still the unknown.
You're praying the gap doesn't work aren't you?

Extremely strange.
 
No, it doesn't. You say "a long time" and then "for some time", which kind of demonstrates that we do not know at what rate the protection from a first dose will decline, how long it will take to decline and so on. I'd have hoped that a government would want to find that out before deciding a policy, but it seems not

We already knew one dose of it would give a decent amount of protection - thats what the first studies found - but how long it lasts is still the unknown.

Based on what is seemingly very high protection after 4 weeks surely you must admit that it’s more likely than not that a decent level of protection must prevail after 12 ?
 
Based on what is seemingly very high protection after 4 weeks surely you must admit that it’s more likely than not that a decent level of protection must prevail after 12 ?

Not really - the study wasn't exactly representative (everyone under it was under 65 and a healthcare worker), and "more likely than not" shouldn't really be a basis for a policy decision that affects that many people (edit: not that it was a basis - they decided this nearly two months before this study came out).

I mean, have the Israelis changed their policy based on this research? No.
 
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