Current Affairs Coronavirus Thread - Serious stuff !!!

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It wont have been given an emergency license n that basis. The license was granted because of the claims of a 90% efficacy rate for the testing group as a whole - all ages.

AZ has been held to account by the Lancet among others for their lack of testing on older groups. That is just a fact.

Yes, and if that report said, say, 40%, I'd be worried and completely with you. Confidence intervals are exactly what they say on the tin and can be the lower end just as easy as the higher end.

But 8% is just completely, totally implausible. To the point where the confidence interval to state that number is about the same as a placebo.

For the same journo to say it's 70% under the age of 65...



... just screams "no chance". The vaccine won't just stop working completely after a certain age - it might diminish, that isn't unheard of at all due to age related immune system responses, but you're talking 10/15% - not a complete tanking of the efficacy to basically nothing.
 
Yes, and if that report said, say, 40%, I'd be worried and completely with you. Confidence intervals are exactly what they say on the tin and can be the lower end just as easy as the higher end.

But 8% is just completely, totally implausible. To the point where the confidence interval to state that number is about the same as a placebo.

For the same journo to say it's 70% under the age of 65...



... just screams "no chance". The vaccine won't just stop working completely after a certain age - it might diminish, that isn't unheard of at all due to age related immune system responses, but you're talking 10/15% - not a complete tanking of the efficacy to basically nothing.

Yeah if they had said 8% reduction in efficiency for over 65s I could understand it, this dramatic drop off combined with no-one being prepared to go on the record, has red flags all over it.
 
Yeah if they had said 8% reduction in efficiency for over 65s I could understand it, this dramatic drop off combined with no-one being prepared to go on the record, has red flags all over it.

To be blunt, for that 8% to be correct, alongside 70% for younger groups, humans would have to turn into a different species on their 65th birthday. It's that implausible.
 
Well it looks like being a great night here in Covid fairyland, but some of us are helping with Zoom lessons for 7 year olds tomorrow. In Science they are answering the question, ‘why would the Germans attempt to undermine a British vaccine costing x20 times less than a German vaccine’......should be good......

Why would Pete believe a story in the equivalent of the German Scum speaks for the EU.

Last time i checked Sweden was in the EU.
 
Yes, and if that report said, say, 40%, I'd be worried and completely with you. Confidence intervals are exactly what they say on the tin and can be the lower end just as easy as the higher end.

But 8% is just completely, totally implausible. To the point where the confidence interval to state that number is about the same as a placebo.

For the same journo to say it's 70% under the age of 65...



... just screams "no chance". The vaccine won't just stop working completely after a certain age - it might diminish, that isn't unheard of at all due to age related immune system responses, but you're talking 10/15% - not a complete tanking of the efficacy to basically nothing.

I think there’s a mix up. 8% was the sample size of over 65s in the AZ study, rather than the efficacy.
 
I think there’s a mix up. 8% was the sample size of over 65s in the AZ study, rather than the efficacy.

This seems plausible. German gov have said they don’t want to approve for over 65s due to the small sample size of 8%, which is reasonable.

Our own clinical advice says that conclusions on efficacy can’t be drawn in the over 65 cohort due to small sample size, but we approved as there is some evidence of immuno response.

Tabloid journalist totally misunderstands, and prints.
 
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