Current Affairs Coronavirus Thread - Serious stuff !!!

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Kenshin said:
As I said above , the disease exists and has done for years. Up to 1000 kids affected in the UK last year.

The way it is being reported , like it has just magically started happening since covid-19 existed.

Which isn't exactly true.
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There could well be issues with media reporting but doctors themselves seem to be describing something that, whilst it shares some characteristics with Kawasaki disease, differs in important aspects. There certainly does seem to be a huge jump in incidents (19 in 5 years vs 10 in 2 months) that happened concurrent with the coronavirus outbreak. It may just be random chance but seeing similar jumps in other coronavirus hard hit areas like New York would suggest the link is at the very least worth exploring.
Background
The Bergamo province, which is extensively affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic, is a natural observatory of virus manifestations in the general population. In the past month we recorded an outbreak of Kawasaki disease; we aimed to evaluate incidence and features of patients with Kawasaki-like disease diagnosed during the SARS-CoV-2 epidemic.
Methods
All patients diagnosed with a Kawasaki-like disease at our centre in the past 5 years were divided according to symptomatic presentation before (group 1) or after (group 2) the beginning of the SARS-CoV-2 epidemic. Kawasaki- like presentations were managed as Kawasaki disease according to the American Heart Association indications. Kawasaki disease shock syndrome (KDSS) was defined by presence of circulatory dysfunction, and macrophage activation syndrome (MAS) by the Paediatric Rheumatology International Trials Organisation criteria. Current or previous infection was sought by reverse-transcriptase quantitative PCR in nasopharyngeal and oropharyngeal swabs, and by serological qualitative test detecting SARS-CoV-2 IgM and IgG, respectively.
Findings
Group 1 comprised 19 patients (seven boys, 12 girls; aged 3·0 years [SD 2·5]) diagnosed between Jan 1, 2015, and Feb 17, 2020. Group 2 included ten patients (seven boys, three girls; aged 7·5 years [SD 3·5]) diagnosed between Feb 18 and April 20, 2020; eight of ten were positive for IgG or IgM, or both. The two groups differed in disease incidence (group 1 vs group 2, 0·3 vs ten per month), mean age (3·0 vs 7·5 years), cardiac involvement (two of 19 vs six of ten), KDSS (zero of 19 vs five of ten), MAS (zero of 19 vs five of ten), and need for adjunctive steroid treatment (three of 19 vs eight of ten; all p<0·01).
Interpretation
In the past month we found a 30-fold increased incidence of Kawasaki-like disease. Children diagnosed after the SARS-CoV-2 epidemic began showed evidence of immune response to the virus, were older, had a higher rate of cardiac involvement, and features of MAS. The SARS-CoV-2 epidemic was associated with high incidence of a severe form of Kawasaki disease. A similar outbreak of Kawasaki-like disease is expected in countries involved in the SARS-CoV-2 epidemic.
 
Interesting article on weather and coronavirus.
New research has bolstered the hypothesis that summer’s heat, humidity, abundant sunshine and opportunities for people to get outside should combine to inhibit — though certainly not halt — the spread of the coronavirus. But infectious disease experts add a cautionary note: Any benefit from summer conditions would likely be lost if people mistakenly believe the virus can’t spread in warm weather and abandon efforts that limit infections, such as social distancing.
 
LinekersLegs said:
There could well be issues with media reporting but doctors themselves seem to be describing something that, whilst it shares some characteristics with Kawasaki disease, differs in important aspects. There certainly does seem to be a huge jump in incidents (19 in 5 years vs 10 in 2 months) that happened concurrent with the coronavirus outbreak. It may just be random chance but seeing similar jumps in other coronavirus hard hit areas like New York would suggest the link is at the very least worth exploring.
Background
The Bergamo province, which is extensively affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic, is a natural observatory of virus manifestations in the general population. In the past month we recorded an outbreak of Kawasaki disease; we aimed to evaluate incidence and features of patients with Kawasaki-like disease diagnosed during the SARS-CoV-2 epidemic.
Methods
All patients diagnosed with a Kawasaki-like disease at our centre in the past 5 years were divided according to symptomatic presentation before (group 1) or after (group 2) the beginning of the SARS-CoV-2 epidemic. Kawasaki- like presentations were managed as Kawasaki disease according to the American Heart Association indications. Kawasaki disease shock syndrome (KDSS) was defined by presence of circulatory dysfunction, and macrophage activation syndrome (MAS) by the Paediatric Rheumatology International Trials Organisation criteria. Current or previous infection was sought by reverse-transcriptase quantitative PCR in nasopharyngeal and oropharyngeal swabs, and by serological qualitative test detecting SARS-CoV-2 IgM and IgG, respectively.
Findings
Group 1 comprised 19 patients (seven boys, 12 girls; aged 3·0 years [SD 2·5]) diagnosed between Jan 1, 2015, and Feb 17, 2020. Group 2 included ten patients (seven boys, three girls; aged 7·5 years [SD 3·5]) diagnosed between Feb 18 and April 20, 2020; eight of ten were positive for IgG or IgM, or both. The two groups differed in disease incidence (group 1 vs group 2, 0·3 vs ten per month), mean age (3·0 vs 7·5 years), cardiac involvement (two of 19 vs six of ten), KDSS (zero of 19 vs five of ten), MAS (zero of 19 vs five of ten), and need for adjunctive steroid treatment (three of 19 vs eight of ten; all p<0·01).
Interpretation
In the past month we found a 30-fold increased incidence of Kawasaki-like disease. Children diagnosed after the SARS-CoV-2 epidemic began showed evidence of immune response to the virus, were older, had a higher rate of cardiac involvement, and features of MAS. The SARS-CoV-2 epidemic was associated with high incidence of a severe form of Kawasaki disease. A similar outbreak of Kawasaki-like disease is expected in countries involved in the SARS-CoV-2 epidemic.
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That's not all entirely true though

https://www.societi.org.uk/

That says there was 1000 cases in the UK last year. So it isn't a huge surge in cases of it all of a sudden, potentially instead cases that would have happened anyway but being highlighted.

More to the point, it's either Kawasaki disease or it isn't . If it is then it exists before all of this in significant numbers. If it's entirely new then calling it by that name is very misleading and not actually reporting it correctly.
 
Kenshin said:
That's not all entirely true though

https://www.societi.org.uk/

That says there was 1000 cases in the UK last year. So it isn't a huge surge in cases of it all of a sudden, potentially instead cases that would have happened anyway but being highlighted.

More to the point, it's either Kawasaki disease or it isn't . If it is then it exists before all of this in significant numbers. If it's entirely new then calling it by that name is very misleading and not actually reporting it correctly.
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A 30 fold increase in Bergamo cases is most definitely a huge spike, at least in that city.

I found this interview informative interviewhttps://www.vox.com/today-explained) with this pediatrician
http://www.childrenshospital.org/directory/physicians/f/kevin-g-friedman whose bio states “My clinical focuses are echocardiography, particularly fetal echocardiography, management of congenital heart disease, and Kawasaki Disease.“ He describes in London a “cluster of cases which seemed way out proportion to normal incidence“ that was reviewed by other in the field.

He also said that they aren’t calling it Kawasaki among doctors - PIMS was what I think he said.
 
LinekersLegs said:
A 30 fold increase in Bergamo cases is most definitely a huge spike, at least in that city.

I found this interview informative interviewhttps://www.vox.com/today-explained) with this pediatrician
http://www.childrenshospital.org/directory/physicians/f/kevin-g-friedman whose bio states “My clinical focuses are echocardiography, particularly fetal echocardiography, management of congenital heart disease, and Kawasaki Disease.“ He describes in London a “cluster of cases which seemed way out proportion to normal incidence“ that was reviewed by other in the field.

He also said that they aren’t calling it Kawasaki among doctors - PIMS was what I think he said.
Click to expand...
See but the official website doesn't say that, it talks about 1000 UK cases alone.

By singling it to one particular city and saying there is a rise there is neither here nor there. It can happen anytime anywhere given the disease is triggered rather than developed.

There may be a rise this year in the UK , we wouldn't know that until next year. Given we get around 1000 cases anyway , we are far shy of that target coming up to 6 months in if there has only been 100.

If people aren't calling it that in the right fields then it's everyone else mis diagnosing it essentially. So the story has no merit despite it being printed / published everywhere. Noone would have heard of Kawasaki disease until around 3 weeks ago. All of a sudden its the new buzzword to describe covid-19 in relation to kids.

As I say it's either Kawasaki or it isn't. If it isn't then the media are pretty much lying to the people about what's going on. You can't call mis labeled diseases occuring as any other capacity than lying. It's like saying someone has one thing when it's another. Sars is similar to covid-19, they aren't the same.
 
Kenshin said:
See but the official website doesn't say that, it talks about 1000 UK cases alone.

By singling it to one particular city and saying there is a rise there is neither here nor there. It can happen anytime anywhere given the disease is triggered rather than developed.

There may be a rise this year in the UK , we wouldn't know that until next year. Given we get around 1000 cases anyway , we are far shy of that target coming up to 6 months in if there has only been 100.

If people aren't calling it that in the right fields then it's everyone else mis diagnosing it essentially. So the story has no merit despite it being printed / published everywhere. Noone would have heard of Kawasaki disease until around 3 weeks ago. All of a sudden its the new buzzword to describe covid-19 in relation to kids.

As I say it's either Kawasaki or it isn't. If it isn't then the media are pretty much lying to the people about what's going on. You can't call mis labeled diseases occuring as any other capacity than lying. It's like saying someone has one thing when it's another. Sars is similar to covid-19, they aren't the same.
Click to expand...
I've only heard descriptions of a 'Kawasaki like disease'
 
Kenshin said:
See but the official website doesn't say that, it talks about 1000 UK cases alone.

By singling it to one particular city and saying there is a rise there is neither here nor there. It can happen anytime anywhere given the disease is triggered rather than developed.

There may be a rise this year in the UK , we wouldn't know that until next year. Given we get around 1000 cases anyway , we are far shy of that target coming up to 6 months in if there has only been 100.

If people aren't calling it that in the right fields then it's everyone else mis diagnosing it essentially. So the story has no merit despite it being printed / published everywhere. Noone would have heard of Kawasaki disease until around 3 weeks ago. All of a sudden its the new buzzword to describe covid-19 in relation to kids.

As I say it's either Kawasaki or it isn't. If it isn't then the media are pretty much lying to the people about what's going on. You can't call mis labeled diseases occuring as any other capacity than lying. It's like saying someone has one thing when it's another. Sars is similar to covid-19, they aren't the same.
Click to expand...
The doctors in the field have and they have categorically stated they have seen a jump in similar (but not exactly the same) symptoms as Kawasaki disease and they believe it is linked to coronavirus. I’m still not quite sure what point you are trying to argue and since I have just been handed a rather nice drink I’ll leave it to another day to try to decipher it, good night.
 
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