Current Affairs Coronavirus Thread - Serious stuff !!!

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Genuine question I was multi tasking whilst listening to this and as I’m a man it was always going to end in tears . I heard whitty try and explain why the SA data of potential ‘mildness’ shouldn’t be universally taken, namely because they had “immunity from a delta wave “ or something like that .i might have heard that wrong but My problem is don’t we have similar immunity ?
 
Genuine question I was multi tasking whilst listening to this and as I’m a man it was always going to end in tears . I heard whitty try and explain why the SA data of potential ‘mildness’ shouldn’t be universally taken, namely because they had “immunity from a delta wave “ or something like that .i might have heard that wrong but My problem is don’t we have similar immunity ?
I think the main point he was making is that although the numbers of hospitalisations are lower potentially because of built up immunity, if the variant continues to rise exponentially, hospitalisations and then deaths will rise in line. If the peak number of cases is twice as high but half the number are hospitalised from this variant than Delta, then the same amount of people will end up in hospital.
 
I think the main point he was making is that although the numbers of hospitalisations are lower potentially because of built up immunity, if the variant continues to rise exponentially, hospitalisations and then deaths will rise in line. If the peak number of cases is twice as high but half the number are hospitalised from this variant than Delta, then the same amount of people will end up in hospital.
No I got that bit about doubling but the previous wave /immunity bit I’m sorry I can’t follow as I don’t understand why they’re different.

Keep in mind i’m quite stupid .
 
We may have similar immunity to SA which will result in less severity of the virus, but it’s way more infectious resulting in potentially a worse scenario.
Again I understand that but I thought he mentioned something like they had immunity due to a previous covid wave , it was that that caught my ear . Perhaps it completely focused on the wrong bit , thanks for taking the time to reply though . Much appreciated.
 
No I got that bit about doubling but the previous wave /immunity bit I’m sorry I can’t follow as I don’t understand why they’re different.

Keep in mind i’m quite stupid .

I didn’t get that point either, but he’s just clarified it in follow up, as being about the difference in immunity levels between delta and omicron for SA and UK.

I.E - SA had no immunity in their Delta wave, but they have some immunity for their omicron versus the UK already had some immunity for our delta wave.

So the difference SA have seen between delta and omicron hospitalisation rates could be attributable to their relative difference in immunity between the 2 waves. Make sense? It’s quite a subtle point.

He did also say, it’s possible the intrinsic severity could have changed, but don’t have the data to show it yet.
 
Genuine question I was multi tasking whilst listening to this and as I’m a man it was always going to end in tears . I heard whitty try and explain why the SA data of potential ‘mildness’ shouldn’t be universally taken, namely because they had “immunity from a delta wave “ or something like that .i might have heard that wrong but My problem is don’t we have similar immunity ?
Wasn’t listening but Whitty may have been pointing out that South Africa this time last year had a Beta wave rather than the Alpha wave that the UK went through. A recent preprint suggested that a lot of the reinfections were in people who had had Delta which is a bit unusual as that was the most recent wave.
https://www.medrxiv.org/content/10.1101/2021.11.11.21266068v2.full.pdf Page 14

So possible that Beta produces a better protection vs Omicron (iirc some of the mutations on the spike protein are similar between the two) but also it could be due to the sheer number of Delta infections skewing things.
 
I didn’t get that point either, but he’s just clarified it in follow up, as being about the difference in immunity levels between delta and omicron for SA and UK.

I.E - SA had no immunity in their Delta wave, but they have some immunity for their omicron versus the UK already had some immunity for our delta wave.

So the difference SA have seen between delta and omicron hospitalisation rates could be attributable to their relative difference in immunity between the 2 waves. Make sense? It’s quite a subtle point.

He did also say, it’s possible the intrinsic severity could have changed, but don’t have the data to show it yet.
Thanks .

I’m still sort of struggling to put it all together but got that , I’ll definitely need a re listen to that clarification as well .
 
Wasn’t listening but Whitty may have been pointing out that South Africa this time last year had a Beta wave rather than the Alpha wave that the UK went through. A recent preprint suggested that a lot of the reinfections were in people who had had Delta which is a bit unusual as that was the most recent wave.
https://www.medrxiv.org/content/10.1101/2021.11.11.21266068v2.full.pdf Page 14

So possible that Beta produces a better protection vs Omicron (iirc some of the mutations on the spike protein are similar between the two) but also it could be due to the sheer number of Delta infections skewing things.


Thank you so much , should definitely have @ you !

I mean however this is where at school or particularly at I dinner party I would nod sagely like I understand then quickly talk about how hagler vs hearns is probably the best round of boxing ever .
 
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