Current Affairs Coronavirus Thread - Serious stuff !!!

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Hopefully this will be the case.
However, the vaccine will only be effective if it can cause a significant enough response by the adaptive immune system. The live virus seems to cause quite a weak response by the adaptive immune system in most people because they only get mild symptoms for a few days. Maybe that is because their innate immune system works well, but vaccines rely on the adaptive system being triggered to make antibodies.
The lack of effective vaccines against other coronaviruses like sars and mers is what concerns me, which suggests that the immune memory response is not very long lived and protective antibodies may only be present for a couple of years at most.
Not only that, but if this thing behaves like some other viruses such as influenza, rhinoviruses and other coronaviruses then it might mutate sufficiently to avoid the body’s immune memory anyway.
It’s a devious bug this one, and personally I’m a bit concerned that the “lockdown exit strategy” is betting on the availability of a vaccine that may not work, or may not work for long. There is too much talk of a second peak and that it must be avoided...but the reality is that this thing will probably return either because our immune response wears off or because it mutates, and so a second peak or second wave is not really avoidable.
Obviously I hope I’m wrong here.

There is a SARS vaccine.

It may be that you need a series of doses and/or boosters to get titers up. This is why we do the trials and why it may take a while to get an effective vaccine.
 
You may be right, and I hope you are.
The catch with viruses is their mutation rates though, and many antiviral drugs may help reduce the viral load and slow viral replication, but even then the effectiveness of many drugs used against common viruses such as influenzas, herpes and hepatitis viruses have become reduced in effectiveness because of mutation in, say, the DNA polymerase gene of the virus.
We need to pray that we don’t see too much mutation with this coronavirus and any close strains.
A virologist from Queen’s University in Belfast said the virus doesn’t seem to be evolving anywhere near as much as you would expect a flu virus to, for example.
 
Saw something before that said when shops open back up people may only be aloud to shop alone.

Sadly I fear life is going to become very very boring for us all - no shops, bars, eating out, sports, concerts, holidays for a long long time.

Work and home going to be like living in North Korea.
 
Daily testing is up to 43k carried out yesterday (27th). Still unlikely to hit 100k in 2 days time, but the numbers are really ramping up now
 
Saw something before that said when shops open back up people may only be aloud to shop alone.

Sadly I fear life is going to become very very boring for us all - no shops, bars, eating out, sports, concerts, holidays for a long long time.

Work and home going to be like living in North Korea.
It's this for a medium period of time or potential die pretty quickly and possible infect and cause the death of others.

Try to find a hobby that you can devote your time to.
 
The government claims they're following the 'science'. Erm, the 'science'

Q: There is confusion about what the social distancing measures are. Can you clarify them?

Hancock says it is clear; people have to follow the social distancing rules.
What distancing rules?

Robert Dingwall, of the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG), says there has ‘never been a scientific basis for two metres’, naming it a ‘rule of thumb’.

‘There’s never been a scientific basis for two metres, it’s kind of a rule of thumb. But it’s not like there is a whole kind of rigorous scientific literature that it is founded upon.’
No, there is no real scientific basis for the two metres spacing.

It is clear that the greater the distance between peoplethe lower the risk of passing on the infection.

However, the reality is that in a warm and calm environment virus particles generally could be coughed or sneezed for distances closer to nine or ten metres than two.

Also, in still air fine droplets can remain suspended for some time, allowing another person to pass through them and possibly become infected.

This would really mean that you would want spacing of, say, ten metres between people and hope they didn’t cough or sneeze so anyone else walked through their droplet spray.

The net result is that you would have a queue of one and a quarter miles just to allow 200 people into a supermarket, and you’d only want to walk around the shop an hour or so after the last person had done so.

For these impractical distancing and timing measures to be enforced would be difficult and it’s just easier to tell people to stay a couple of metres away and hope! Even then, lots of people don’t actually seem to know what two metres looks like, so they’d have no hope counting all the way to ten.
 
Saw something before that said when shops open back up people may only be aloud to shop alone.

Sadly I fear life is going to become very very boring for us all - no shops, bars, eating out, sports, concerts, holidays for a long long time.

Work and home going to be like living in North Korea.
We’ve also got a sickly fat gimp with a bad haircut in charge
 
No, there is no real scientific basis for the two metres spacing.

It is clear that the greater the distance between peoplethe lower the risk of passing on the infection.

However, the reality is that in a warm and calm environment virus particles generally could be coughed or sneezed for distances closer to nine or ten metres than two.

Also, in still air fine droplets can remain suspended for some time, allowing another person to pass through them and possibly become infected.

This would really mean that you would want spacing of, say, ten metres between people and hope they didn’t cough or sneeze so anyone else walked through their droplet spray.

The net result is that you would have a queue of one and a quarter miles just to allow 200 people into a supermarket, and you’d only want to walk around the shop an hour or so after the last person had done so.

For these impractical distancing and timing measures to be enforced would be difficult and it’s just easier to tell people to stay a couple of metres away and hope! Even then, lots of people don’t actually seem to know what two metres looks like, so they’d have no hope counting all the way to ten.
I've seen a lot of advice where the distance is reduced from 2m to 1m particularly in Asia or Africa.

WHO talks about 1m greetings and the International Red Cross has issued a lot of advice where the distancing advice is 1m.

Personally the further I can be away from people the better.
 
Saw something before that said when shops open back up people may only be aloud to shop alone.

Sadly I fear life is going to become very very boring for us all - no shops, bars, eating out, sports, concerts, holidays for a long long time.

Work and home going to be like living in North Korea.


I have tried to wade through this over the last 4 weeks, couple hours a day here and there but this Act, says to me this is a long haul, there are some disturbing provisions in this, such as the removal of children, prison sentences and movement restrictions.

I am a layman so may not have fully grasped it all and some of it looks far too complex for my brain to fully comprehend but even though there are calls for it to be regularly reviewed it seems this will be with us for some time.

 
There is a SARS vaccine.

It may be that you need a series of doses and/or boosters to get titers up. This is why we do the trials and why it may take a while to get an effective vaccine.
But, and I may be wrong here, there hasn’t been a mass vaccination programme for SARS which the current coronavirus will likely require, because SARS didn’t spread as far or as fast.
So, without a successful mass immunisation against SARS and if the vaccines that were produced then required boosters because they didn’t produce a very long immune memory response, would they really be classed as “effective”?
 
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About time someone spoke out against the government's guidance for sending people back to care homes with coronavirus and advising they're 'isolated'. Seeing how vulnerable care home residents are, and the death toll of those over 60, they should have been treated in hospital from the off.

'Hospital patients with Covid-19 diagnosis should not be discharged into care homes'
Hospital patients should not be discharged into care or nursing homes if they have a Covid-19 diagnosis in order to protect “vulnerable” residents and staff, an expert said.
Carl Heneghan, professor of evidence-based medicine at the University of Oxford, said there is a need to think through the strategy to stabilise infections in nursing homes.
Discharging patients with confirmed Covid-19 into care settings and isolating them, as set out in Government guidance “just does not make any sense” clinically, he said.
He told the Science Media Centre he understands about a third of nursing homes have Covid-19 outbreaks.
Discharging hospital patients with Covid-19 into those without the virus “has got to be an utter no-no”, he said.
He added: “If that continues, we will have a problem if we transfer people from hospital in the home setting, there must be a line drawn to say these people have no active infection.”
 
I've seen a lot of advice where the distance is reduced from 2m to 1m particularly in Asia or Africa.

WHO talks about 1m greetings and the International Red Cross has issued a lot of advice where the distancing advice is 1m.

Personally the further I can be away from people the better.
That’s true, but that “advice” is being given for practical and logistical reasons rather than because there is scientific evidence that says that you won’t transmit the virus from more than one or two metres away.
 
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