I know it will work because I am brill. Your motherboard specs show it will take RAM up to a speed of PC5300 (basically the PC5300 is the branding for the speed it runs at) and the RAM I linked is PC5300. The motherboard will support 4 1 gig sticks. This is only 2 1 gig sticks. And yes, all you have to do is pull the old stuff out and put this in, no software to run.
If you go to the SPD tab in CPU-Z it should tell you the type of RAM you have installed right now, so we can tell if you will still be able to use it as RAM or paperweights.