McCarthy, who missed Everton’s 1-0 win over Stoke City and was forced to pull out of the Republic of Ireland’s squad for the opening World Cup qualifier in Serbia, is now doubtful for a further five games before returning to action.
McCarthy’s compatriot Seamus Coleman however, has been declared fit to start Monday’s Premier League fixture at Sunderland.
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Koeman: “James McCarthy has had groin surgery and will be out for three weeks.
“Seamus was fit to play and he has come back without any reaction. He is now fit to start.”