Portugal has shown that by legalizing you make it far, far easier to help people and get them into treatment. They have way less people dependant on hard drugs now because they can address the problem openly instead of it all being underground. You treat people as sick rather than criminals. Locking people up is utterly pointless. You can get drugs in jail. Not to mention if you can get drugs in jail then how can prohibition ever succeed if the most secure facilities we can possibly build can't be kept drug free? Putting people in jail doesn't work -- they are MORE likely to go back to drugs when they are released.
As an aside: If the war on drugs is a real "war" then what the US and Mexico did in their attempt to boost the war on drugs in 2006 (which most people estimate has caused around 50,000 deaths) should be considered a war crime. It's an absolute disgrace and its supported by people who just have attitudes like "drugs are bad m'kay" and don't actually consider the real world impact of policies which that viewpoint allows governments to pursue.
I don't know how people can play the "morality" card on one hand and then turn a blind eye to the sickening damage which prohibition actually does to people around the world. Latin America is starting to fight back as well -- they are sick of having their people die because people in the US, England etc. still support prohibition and are happy to turn a blind eye to the deaths they cause thousands of miles away.
http://www.outsidethebeltway.com/latin-american-leaders-question-war-on-drugs-in-u-n-speeches/
Escobar was supposedly the ninth richest person in the world at one point and head of a massive organization. When they finally killed him it barely put a dent in the illegal drug trade because there was still demand. Others just replaced him. If you eliminated the demand by making it legal then when you kill these people (or put them in jail) there is nobody left to replace them because all of a sudden the bottom has fallen out of the illegal drug market. Then you can address the addicts with treatment options people feel safe to pursue because they know they won't be locked up for admitting they are addicts. You can also funnel some of the massive cost of policing drugs into treatment. It works. It has worked.
Prohibition doesn't help people get better (actually makes them more likely to stay addicted) and it doesn't stop the flow of the product. So what's the point? We've been doing it for decades now ... why would it suddenly work now? What new ideas are there on the pro-prohibition side? Sell me on prohibition 2013 ... what new ideas are there to replace the ones which have ravaged South America, cost hundreds of thousands of lives, imprisoned millions of people, failed to stop the flow of drugs and failed to lower drug addiction rates? What's new?
Same deal for prostitution by the way even though I got sidetracked by drugs and booze. Legality means you can shine a light on human trafficking, STDs, pimps etc.
I honestly believe ending prohibition is the only moral choice -- those who oppose it are putting their personal feelings over the real world evidence of what will truly help the problem and end the suffering for a lot of people. It will save us money and it will save lives.