United have finished below 3rd in 21 years. I expect Mourinho picks up his old form at Chelsea. I have no idea what City does with their new manager, but they have talent on the squad. Of these, I can't imagine all three have great league seasons. Wenger's Arsenal will be solid as ever, but look unlikely to finish above 3rd. Spurs could be great, unless we've already seen the best of them. I won't expect anything out of Rodgers' RS until I see it on the table.
Injuries, transfer requests, baby momma drama (John Terry still plays?), and new management fumbles are all reasons to expect something unusual this year. That said, Everton have got a new manager too, so these affect everyone. I'll opine on the Blues' finish after the transfer window closes.