You absolutely cannot sit Gueye and Schneiderlin in this. Its a fantasy that we have good enough DMs without them. You need at least one of them. Besic is NOT on the same level. I think you have to play DCL up top, hes just been better than Sandro, and play one less DM and pair him with Rooney. I think you need to bring in either Vlasic or Lookman on one of the sides., then you have Siggy and Klaassen as the other two attackers for a total of 5.
But I bet its Rooney up top, with Siggy on the left, Klaassen in the middle, and DCL on the right. With two DMs.